IL5

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IL5
[[Image:{{{Image}}}\|thumb\|220px\|2D structure for IL5]]
Chemical Name
Chemical Formula
CAS Number
Chemical Information
Biochemical Taxonomy
Functional Taxonomy
Nutritional Taxonomy
Metabolic Pathways
Biofluid Location
Tissue Location
Normal Biofluid Concentrations
Normal Tissue Concentrations
Diseases / Conditions Related to Nutrition
Other (Monogenic Disorders)
Abnormal Biofluid Concentrations
Abnormal Tissue Concentrations
Physiological Processes

Authors:	L. Pellis
Affiliations:	TNO, the Netherlands

1 Introduction
2 Biological Function
3 Catabolism
4 Diseases / Conditions Related to Nutrition
- 4.1 Associated decreased protein/metabolite profile
- 4.2 Associated increased protein/metabolite profile
5 Other (Monogenic) Disorders
6 Nutritional Information
7 Drivers for biological variation
8 Vulnerable groups
9 Other resources
10 Links

Introduction

guidelines

Human Interleukin-5

Interleukin 5 is produced by T-cells. It is a specific hematopoietic growth factor that is responsible for the growth and differentiation of eosinophils. It also promotes the generation of cytotoxic T-cells from thymocytes.

Rodent Interleukin-5

IL-5, produced by T-cells, is a specific hematopoietic growth factor that is responsible for growth and differentiation of eosinophils. It also promotes the generation of cytotoxic T-cells from thymocytes. A possible clinical application is suggested by the activity of IL-5 on eosinophils. Animal experiments have shown that eosinophilia elicited by nematode infections in mice and the concomitant infiltration of the lung with eosinophils can be prevented by administration of monoclonal animals directed against IL-5.