S-(2-Methylbutanoyl)-dihydrolipoamide

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S-(2-Methylbutanoyl)-dihydrolipoamide
File:HMDB06869.png
2D structure for S-(2-Methylbutanoyl)-dihydrolipoamide
Chemical Name S-(8-amino-8-oxo-3-sulfanyloctyl) 2-methylbutanethioate
Chemical Formula C13H25NO2S2
CAS Number
Chemical Information HMDB06869
Biochemical Taxonomy

  • Lipoamides and Derivatives

Functional Taxonomy Not Available
Nutritional Taxonomy Not Available
Metabolic Pathways

  • Valine, Leucine and Isoleucine Degradation

Biofluid Location Not Available
Tissue Location Not Available
Normal Biofluid Concentrations Not Available
Normal Tissue Concentrations Not Available
Diseases / Conditions Related to Nutrition Not Available
Other (Monogenic Disorders) Not Available
Abnormal Biofluid Concentrations Not Available
Abnormal Tissue Concentrations Not Available
Physiological Processes Not Available
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Contents

Introduction

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S-(2-Methylbutanoyl)-dihydrolipoamide-E is an intermediate in isoleucine degradation. S-(2-Methylbutanoyl)-dihydrolipoamide is normally conjugated to a lysine residue of the methylpropanoyltransferase enzyme (E stands for enzyme). The structure shown here is the free form. Specifically S-(2-Methylbutanoyl)-dihydrolipoamide-E is the 2-methylbutanoyl thioester of the reduced lipoyllysine residue in dihydrolipoyllysine-residue (2-methylpropanoyl)transferase.

Biological Function

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Catabolism

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Diseases / Conditions Related to Nutrition

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Other (Monogenic) Disorders

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Nutritional Information

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Drivers for biological variation

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Vulnerable groups

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Other resources

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Links

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