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The NuGOwiki Metabolite Database is a joint initiative of NuGO and HMDB
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| S-(3-Methylbutanoyl)-dihydrolipoamide-E | |
|---|---|
| File:HMDB06867.png 2D structure for S-(3-Methylbutanoyl)-dihydrolipoamide-E | |
| Chemical Name | |
| Chemical Formula | C13H25NO2S2 |
| CAS Number | |
| Chemical Information | HMDB06867 |
| Biochemical Taxonomy |
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| Functional Taxonomy | Not Available |
| Nutritional Taxonomy | Not Available |
| Metabolic Pathways |
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| Biofluid Location | Not Available |
| Tissue Location | Not Available |
| Normal Biofluid Concentrations | Not Available |
| Normal Tissue Concentrations | Not Available |
| Diseases / Conditions Related to Nutrition | Not Available |
| Other (Monogenic Disorders) | Not Available |
| Abnormal Biofluid Concentrations | Not Available |
| Abnormal Tissue Concentrations | Not Available |
| Physiological Processes | Not Available |
| Authors: | |
| Affiliations: |
Contents |
Introduction
guidelines
S-(3-Methylbutanoyl)-dihydrolipoamide-E is an intermediate in valine, leucine and isoleucine degradation(KEGG ID C15975 ). It is the second to last step in the synthesis of branched chain fatty acid and is converted from 3-methyl-hydroxybutyl-ThPP via the enzyme 2-oxoisovalerate dehydrogenase [EC:1.2.4.4]. It is then converted to 3-methylbutanoyl-CoA via the enzyme dihydrolipoyllysine-residue (2-methylpropanoyl)transferase[EC:2.3.1.168].
Biological Function
Catabolism
Diseases / Conditions Related to Nutrition
Other (Monogenic) Disorders