Decanoyl-CoA (n-C10:0CoA)

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Decanoyl-CoA (n-C10:0CoA)
File:HMDB06404.png 2D structure for Decanoyl-CoA (n-C10:0CoA)
Chemical Name	S-[2-[3-[[(2R)-4-[[[(2R,3S,4R,5R)-5-(6-aminopurin-9-yl)-4-hydroxy-3-phosphonooxyoxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-hydroxyphosphoryl]oxy-2-hydroxy-3,3-dimethylbutanoyl]amino]propanoylamino]ethyl] decanethioate
Chemical Formula	C₃₁H₅₄N₇O₁₇P₃S
CAS Number	1264-57-9
Chemical Information	HMDB06404
Biochemical Taxonomy	Coenzyme A Derivatives
Functional Taxonomy	Lipid Biosynthesis, Fatty Acid Transport
Nutritional Taxonomy	Not Available
Metabolic Pathways	Fatty Acid Elongation In Mitochondria Fatty Acid Metabolism
Biofluid Location	Not Available
Tissue Location	Not Available
Normal Biofluid Concentrations	Not Available
Normal Tissue Concentrations	Not Available
Diseases / Conditions Related to Nutrition	Not Available
Other (Monogenic Disorders)	Not Available
Abnormal Biofluid Concentrations	Not Available
Abnormal Tissue Concentrations	Not Available
Physiological Processes	Not Available

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Introduction

guidelines
Decanoyl CoA is a human liver acyl-CoA ester. It is selected to determine apparent kinetic constants for human liver acyl-CoA due to its relevance to the human diseases with cellular accumulation of this esters, especially to metabolic defects in the acyl-CoA dehydrogenation steps of the branched-chain amino acids, lysine, 5-hydroxy lysine, tryptophan, and fatty acid oxidation pathways. It is concluded that the substrate concentration is decisive for the glycine conjugate formation and that the occurrence in urine of acylglycines reflects an intramitochondrial accumulation of the corresponding acyl-CoA ester. (PMID: 3707752)