Lactosylceramide (d18:1/12:0)

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Lactosylceramide (d18:1/12:0)
2D structure for Lactosylceramide (d18:1/12:0)
Chemical Name	N-[(E)-1-[(2R,3R,4R,5R,6R)-3,4-dihydroxy-6-(hydroxymethyl)-5-[(3R,4S,5R,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-oxan-2-yl]oxy-3-hydroxy-octadec-4-en-2-yl]octadecanamide
Chemical Formula	C₄₂H₇₉NO₁₃
CAS Number	4682-48-8
Chemical Information	HMDB04866
Biochemical Taxonomy	Glycolipids
Functional Taxonomy	Not Available
Nutritional Taxonomy	Not Available
Metabolic Pathways	Aminosugars Metabolism Galactose Metabolism Glycerolipid Metabolism Glycosphingolipid Metabolism
Biofluid Location	Blood
Tissue Location	Brain Fibroblasts Nerve Cells Neurons Adrenal Gland
Normal Biofluid Concentrations	Blood: 4.5 +/- 1.0 uM
Normal Tissue Concentrations	Not Available
Diseases / Conditions Related to Nutrition	Abetalipoproteinemia Hypobetalipoproteinemia
Other (Monogenic Disorders)	Not Available
Abnormal Biofluid Concentrations	Blood (Abetalipoproteinemia): 3.0 (2.9-3.3) uM Blood (Hypobetalipoproteinemia): 2.5 (2.7-2.8) uM
Abnormal Tissue Concentrations	Not Available
Physiological Processes	Not Available

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Introduction

guidelines
A glycosphingolipid (ceramide and oligosaccharide)or oligoglycosylceramide with one or more sialic acids (i.e. n-acetylneuraminic acid) linked on the sugar chain. It is a component the cell plasma membrane which modulates cell signal transduction events. Gangliosides have been found to be highly important in immunology. Ganglioside GL2a carries a net-negative charge at pH 7.0 and is acidic. Gangliosides can amount to 6% of the weight of lipids from brain, but they are found at low levels in all animal tissues.