3,4-Dihydroxymandelic acid

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3,4-Dihydroxymandelic acid
2D structure for 3,4-Dihydroxymandelic acid
Chemical Name 2-(3,4-dihydroxyphenyl)-2-hydroxy-acetic acid
Chemical Formula C8H8O5
CAS Number 775-01-9
Chemical Information HMDB01866
Biochemical Taxonomy

  • Catecholamines and Derivatives

Functional Taxonomy Not Available
Nutritional Taxonomy Not Available
Metabolic Pathways Not Available
Biofluid Location

  • Blood

Tissue Location

  • Nerves

Normal Biofluid Concentrations

  • Blood: 0.011 +/- 0.004 umol/L

Normal Tissue Concentrations Not Available
Diseases / Conditions Related to Nutrition Not Available
Other (Monogenic Disorders) Not Available
Abnormal Biofluid Concentrations Not Available
Abnormal Tissue Concentrations Not Available
Physiological Processes Not Available
Authors:
Affiliations:

Contents

Introduction

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3,4-Dihydroxymandelic acid is is a minor metabolite of norepinephrine in humans (PMID 12649306). Patients with neuroblastoma experience elevated levels of 3,4-Dihydroxymandelic acid and other Catecholamines metabolites, and their presence in urine is a good indicator for diagnosis and follow-up (PMID 8193481)

Biological Function

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Catabolism

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Diseases / Conditions Related to Nutrition

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Other (Monogenic) Disorders

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Nutritional Information

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Drivers for biological variation

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Vulnerable groups

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Other resources

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Links

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