Pyridoxal 5'-phosphate

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Pyridoxal 5'-phosphate
2D structure for Pyridoxal 5'-phosphate
Chemical Name	(4-formyl-5-hydroxy-6-methyl-pyridin-3-yl)methoxyphosphonic acid
Chemical Formula	C₈H₁₀NO₆P
CAS Number	54-47-7
Chemical Information	HMDB01491
Biochemical Taxonomy	Pyridoxals and Derivatives
Functional Taxonomy	Coenzyme
Nutritional Taxonomy	Not Available
Metabolic Pathways	Alanine and Aspartate Metabolism Butanoate Metabolism Glycine, Serine and Threonine Metabolism Glycosphingolipid Metabolism Lysine Degradation Methionine Metabolism One Carbon Pool by Folate Pantothenate and CoA Biosynthesis Starch and Sucrose Metabolism Valine, Leucine and Isoleucine Biosynthesis Valine, Leucine and Isoleucine Degradation Vitamin B6 Metabolism
Biofluid Location	Blood
Tissue Location	Kidney Liver Muscle Neurons Erythrocyte
Normal Biofluid Concentrations	Blood: 0.042 (0.0076-1.26) umol/L Blood: 0.046 (0.035-0.06) uM Blood: 0.056 +/- 0.042 uM Blood: 0.061 +/- 0.052 uM Blood: 0.068 +/- 0.015 uM Blood: 0.075 +/- 0.022 uM
Normal Tissue Concentrations	Not Available
Diseases / Conditions Related to Nutrition	Patients with rheumatoid arthritis
Other (Monogenic Disorders)	Hyperoxaluria, primary, type I OMIM: 259900
Abnormal Biofluid Concentrations	Blood (Patients with rheumatoid arthritis): 0.024 (0.019-0.031) uM
Abnormal Tissue Concentrations	Not Available
Physiological Processes	Not Available

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Introduction

guidelines
This is the active form of vitamin B6 serving as a coenzyme for synthesis of amino acids, neurotransmitters (serotonin, norepinephrine), sphingolipids, aminolevulinic acid. During transamination of amino acids, pyridoxal phosphate is transiently converted into pyridoxamine phosphate (pyridoxamine). -- Pubchem; Pyridoxal-phosphate (PLP, pyridoxal-5'-phosphate) is a cofactor of many enzymatic reactions. It is the active form of vitamin B6 which comprises three natural organic compounds, pyridoxal, pyridoxamine and pyridoxine. -- Wikipedia