NADH

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NADH
2D structure for NADH
Chemical Name	[(2R,3R,4R,5R)-5-(6-aminopurin-9-yl)-3,4-dihydroxy-oxolan-2-yl]methoxy-[[(2R,3R,4R,5R)-5-(3-carbamoyl-4H-pyridin-1-yl)-3,4-dihydroxy-oxolan-2-yl]methoxy-hydroxy-phosphoryl]oxy-phosphinic acid
Chemical Formula	C₂₁H₂₉N₇O₁₄P₂
CAS Number	58-68-4
Chemical Information	HMDB01487
Biochemical Taxonomy	Nucleotides
Functional Taxonomy	Not Available
Nutritional Taxonomy	Not Available
Metabolic Pathways	Aminosugars Metabolism Androgen and Estrogen Metabolism Benzoate Degradation via CoA Ligation Bile Acid Biosynthesis Biosynthesis of Steroids Butanoate Metabolism C21-Steroid Hormone Metabolism Fatty Acid Biosynthesis (Path 2) Fatty Acid Metabolism Folate Biosynthesis Fructose and Mannose Metabolism Galactose Metabolism Glutathione Metabolism Glycerolipid Metabolism Glycerophospholipid Metabolism Glycine, Serine and Threonine Metabolism Glycolysis Glyoxylate and Dicarboxylate Metabolism Inositol Metabolism Lysine Degradation Nicotinate and Nicotinamide Metabolism One Carbon Pool by Folate Oxidative Phosphorylation Pentose and Glucuronate Interconversions Porphyrin and Chlorophyll Metabolism Propanoate Metabolism Prostaglandin and Leukotriene Metabolism Purine Metabolism Pyruvate Metabolism Reductive Carboxylate Cycle (CO2 Fixation) Retinol Metabolism Starch and Sucrose Metabolism Synthesis and Degradation of Ketone Bodies Ubiquinone Biosynthesis Valine, Leucine and Isoleucine Biosynthesis Valine, Leucine and Isoleucine Degradation Vitamin B6 Metabolism
Biofluid Location	Blood
Tissue Location	Brain Fibroblasts Muscle Platelet Bladder
Normal Biofluid Concentrations	Blood: 22.0 (14.0-40.0) uM
Normal Tissue Concentrations	Not Available
Diseases / Conditions Related to Nutrition	Not Available
Other (Monogenic Disorders)	Mitochondrial complex i deficiency OMIM: 252010
Abnormal Biofluid Concentrations	Not Available
Abnormal Tissue Concentrations	Not Available
Physiological Processes	Not Available

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Introduction

guidelines
NADH is the reduced form of NAD+, and NAD+ is the oxidized form of NADH, A coenzyme composed of ribosylnicotinamide 5'-diphosphate coupled to adenosine 5'-phosphate by pyrophosphate linkage. It is found widely in nature and is involved in numerous enzymatic reactions in which it serves as an electron carrier by being alternately oxidized (NAD+) and reduced (NADH). It forms NADP with the addition of a phosphate group to the 2' position of the adenosyl nucleotide through an ester linkage.(Dorland, 27th ed)