Thromboxane A2

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Thromboxane A2
2D structure for Thromboxane A2
Chemical Name	7-[3-(3-hydroxyoct-1-enyl)-4,6-dioxabicyclo[3.1.1]hept-2-yl]hept-5-enoic acid
Chemical Formula	C₂₀H₃₂O₅
CAS Number	57576-52-0
Chemical Information	HMDB01452
Biochemical Taxonomy	Prostanoids
Functional Taxonomy	Not Available
Nutritional Taxonomy	Not Available
Metabolic Pathways	Prostaglandin and Leukotriene Metabolism
Biofluid Location	Blood
Tissue Location	Smooth Muscle Platelet
Normal Biofluid Concentrations	Blood: 0.00024 +/- 0.000036 uM
Normal Tissue Concentrations	Not Available
Diseases / Conditions Related to Nutrition	Children with an inherited predisposition to coronary heart disease
Other (Monogenic Disorders)	Not Available
Abnormal Biofluid Concentrations	Blood (Children with an inherited predisposition to coronary heart disease): 0.00045 +/- 0.000047 uM
Abnormal Tissue Concentrations	Not Available
Physiological Processes	Not Available

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Introduction

guidelines
An unstable intermediate between the prostaglandin endoperoxides and thromboxane B2. The compound has a bicyclic oxaneoxetane structure. It is a potent inducer of platelet aggregation and causes vasoconstriction. It is the principal component of rabbit aorta contracting substance (RCS).