Niacinamide

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Niacinamide
2D structure for Niacinamide
Chemical Name	pyridine-3-carboxamide
Chemical Formula	C₆H₆N₂O
CAS Number	98-92-0
Chemical Information	HMDB01406
Biochemical Taxonomy	Cyclic Amines
Functional Taxonomy	Not Available
Nutritional Taxonomy	Not Available
Metabolic Pathways	Nicotinate and Nicotinamide Metabolism Purine Metabolism
Biofluid Location	Blood
Tissue Location	Fibroblasts Neurons Pancreas Placenta Skin Spleen Stratum Corneum Bladder
Normal Biofluid Concentrations	Blood: 0.44 +/- 0.0054 umol/L
Normal Tissue Concentrations	Not Available
Diseases / Conditions Related to Nutrition	Not Available
Other (Monogenic Disorders)	Not Available
Abnormal Biofluid Concentrations	Not Available
Abnormal Tissue Concentrations	Not Available
Physiological Processes	Not Available

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Introduction

guidelines
Niacinamide or vitamin B3 is an important compound functioning as a component of the coenzyme NAD. Its primary significance is in the prevention and/or cure of blacktongue and pellagra. Most animals cannot manufacture this compound in amounts sufficient to prevent nutritional deficiency and it therefore must be supplemented through dietary intake. Niacinamide is used to increase the effect of radiation therapy on tumor cells. Niacin (nicotinic acid) and niacinamide, while both labeled as vitamin B3 also have different applications. Niacinamide is useful in arthritis and early-onset type I diabetes while niacin is an effective reducer of high cholesterol levels.