Glyceric acid 1,3-biphosphate

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Glyceric acid 1,3-biphosphate
2D structure for Glyceric acid 1,3-biphosphate
Chemical Name	(2-hydroxy-3-phosphonooxy-propanoyl)oxyphosphonic acid
Chemical Formula	C₃H₈O₁₀P₂
CAS Number	1981-49-3
Chemical Information	HMDB01270
Biochemical Taxonomy	Acyl Phosphates
Functional Taxonomy	Not Available
Nutritional Taxonomy	Not Available
Metabolic Pathways	Not Available
Biofluid Location	Blood Cellular Cytoplasm
Tissue Location	Not Available
Normal Biofluid Concentrations	Blood: 13.5 +/- 2.1 uM Cellular Cytoplasm: 0.4 uM
Normal Tissue Concentrations	Not Available
Diseases / Conditions Related to Nutrition	Not Available
Other (Monogenic Disorders)	Not Available
Abnormal Biofluid Concentrations	Not Available
Abnormal Tissue Concentrations	Not Available
Physiological Processes	Not Available

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Introduction

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1,3-Bisphosphogylcerate (1,3BPG), also known as PGAP, is a 3-carbon organic molecule present in most, if not all living creatures. It primarily exists as a metabolic intermediate in glycolysis during respiration. 1,3BPG have been recognized as regulatory signal implicated in the control of metabolism, oxygen affinity of red cells and other cellular functions. 1,3BPG concentration in erythrocytes changes in a number of pathological conditions, such as Inherited Phosphoglycerate kinase deficiency in erythrocytes (involved in the synthesis and breakdown of 1,3 BPG). (PMID 3555887) 1,3-bisphosphoglycerate is the anion form of bisphosphoglyceric acid. It is phosphorylated at the number 1 and 3 carbons. The result of this phosphorylation gives 1,3BPG important biological properties such as the ability to phosphorylate ADP to form the energy storage molecule ATP.(wikipedia)