Taurochenodesoxycholic acid

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Taurochenodesoxycholic acid
2D structure for Taurochenodesoxycholic acid
Chemical Name 2-[4-(3,7-dihydroxy-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl)pentanoylamino]ethanesulfonic acid
Chemical Formula C26H45NO6S
CAS Number 516-35-8
Chemical Information HMDB00951
Biochemical Taxonomy

  • Steroids and Steroid Derivatives

Functional Taxonomy Not Available
Nutritional Taxonomy Not Available
Metabolic Pathways Not Available
Biofluid Location

  • Bile
  • Blood

Tissue Location Not Available
Normal Biofluid Concentrations

  • Bile: >0.01 uM
  • Blood: 0.30 +/- 0.08 uM

Normal Tissue Concentrations Not Available
Diseases / Conditions Related to Nutrition Not Available
Other (Monogenic Disorders) Not Available
Abnormal Biofluid Concentrations Not Available
Abnormal Tissue Concentrations Not Available
Physiological Processes Not Available
Authors:
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Contents

Introduction

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A bile salt formed in the liver by conjugation of chenodeoxycholate with taurine, usually as the sodium salt. It acts as detergent to solubilize fats in the small intestine and is itself absorbed. It is used as a cholagogue and choleretic.

Biological Function

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Catabolism

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Diseases / Conditions Related to Nutrition

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Other (Monogenic) Disorders

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Nutritional Information

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Drivers for biological variation

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The bile acids glycocholic acid, glycochenodeoxycholic acid and taurochenodeoxycholic acid are associated with glucose homeostasis, shown by Shaham et al (PubMed). These three bile acids (in plasma) changed reproducibly in response to an oral glucose challenge test. The levels more than doubled during the first 30 min. after glucose ingestion and remained elevated for the entire 2 hours.

Vulnerable groups

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Other resources

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Links

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