Histamine

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Histamine
2D structure for Histamine
Chemical Name	2-(3H-imidazol-4-yl)ethanamine
Chemical Formula	C₅H₉N₃
CAS Number	51-45-6
Chemical Information	HMDB00870
Biochemical Taxonomy	Amino Acids
Functional Taxonomy	Not Available
Nutritional Taxonomy	Not Available
Metabolic Pathways	Not Available
Biofluid Location	Blood Cerebrospinal Fluid (CSF) Urine
Tissue Location	Adrenal Medulla Bladder Brain Epidermis Fibroblasts Intestine Kidney Mast Cell Muscle Myelin Nerves Neurons Pancreas Placenta Platelet Skin Spleen Testes Testis Adipose Tissue
Normal Biofluid Concentrations	Blood: 0.00067 (0.00031-0.0022) uM Blood: 0.44 +/- 0.18 uM Blood: 0.50 +/- 0.21 uM Blood: 0.57 +/- 0.27 uM Cerebrospinal Fluid (CSF): 0.087 (0.018-0.270) uM Cerebrospinal Fluid (CSF): 0.38 uM Urine: 0.007 (0.0036-0.011) umol/mmol creatinine
Normal Tissue Concentrations	Not Available
Diseases / Conditions Related to Nutrition	Continuous ambulatory peritoneal dialysis End Stage Renal Failure Haemodialysis Nephrotic syndrome
Other (Monogenic Disorders)	Not Available
Abnormal Biofluid Concentrations	Blood (Continuous ambulatory peritoneal dialysis): 0.0028 (0.0016-0.012) uM Blood (End Stage Renal Failure): 0.0024 (0.0015-0.0032) uM Blood (Haemodialysis): 0.0022 (0.0015-0.028) uM Blood (Nephrotic syndrome): 0.0016 (0.00090-0.0038) uM
Abnormal Tissue Concentrations	Not Available
Physiological Processes	Not Available

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Introduction

guidelines
An amine derived by enzymatic decarboxylation of histidine. It is a powerful stimulant of gastric secretion, a constrictor of bronchial smooth muscle, a vasodilator, and also a centrally acting neurotransmitter.