Linoleic acid

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Linoleic acid
2D structure for Linoleic acid
Chemical Name	9,12-Octadecadienoic acid
Chemical Formula	C₁₈H₃₂O₂
CAS Number	60-33-3
Chemical Information	HMDB00673
Biochemical Taxonomy	Fatty Acids
Functional Taxonomy	Not Available
Nutritional Taxonomy	Essential Amino Acids
Metabolic Pathways	Not Available
Biofluid Location	Blood Cerebrospinal Fluid (CSF)
Tissue Location	Epidermis Erythrocyte Fibroblasts Intestine Kidney Muscle Myelin Placenta Platelet Prostate Skin Spleen Stratum Corneum Adipose Tissue
Normal Biofluid Concentrations	Blood: 110.0 (42.0-370.0) uM Blood: 17.7 +/- 4.7 uM Blood: 23.39 +/- 2.75 uM Cerebrospinal Fluid (CSF): 11.0 +/- 3.0 uM
Normal Tissue Concentrations	Not Available
Diseases / Conditions Related to Nutrition	Gestational Diabetes Mellitus (GDM) Patients with alcoholic liver disease
Other (Monogenic Disorders)	Not Available
Abnormal Biofluid Concentrations	Blood (Gestational Diabetes Mellitus (GDM)): 22.61 +/- 2.80 uM Blood (Patients with alcoholic liver disease): 886.0 +/- 626.6 umol/L
Abnormal Tissue Concentrations	Not Available
Physiological Processes	Not Available

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Introduction

guidelines
Linoleic acid is a doubly unsaturated fatty acid, also known as an omega-6 fatty acid, occurring widely in plant glycosides. In this particular polyunsaturated fatty acid (PUFA), the first double bond is located between the sixth and seventh carbon atom from the methyl end of the fatty acid (n-6). Linoleic acid is an essential fatty acid in human nutrition because it cannot be synthesized by humans. It is used in the biosynthesis of prostaglandins (via arachidonic acid) and cell membranes. (From Stedman, 26th ed)