Phosphoserine

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Phosphoserine
2D structure for Phosphoserine
Chemical Name	(2S)-2-amino-3-phosphonooxy-propanoic acid
Chemical Formula	C₃H₈NO₆P
CAS Number	407-41-0
Chemical Information	HMDB00272
Biochemical Taxonomy	Amino Acid Phosphates
Functional Taxonomy	Not Available
Nutritional Taxonomy	Not Available
Metabolic Pathways	Vitamin B6 Metabolism
Biofluid Location	Blood Cerebrospinal Fluid (CSF) Urine
Tissue Location	Not Available
Normal Biofluid Concentrations	Blood: 17.0 +/- 3.0 umol/L Cerebrospinal Fluid (CSF): 4.2 +/- 1.7 uM Cerebrospinal Fluid (CSF): 5.0 +/- 0.9 uM Urine: 4.605 (1.645-7.566) umol/mmol creatinine
Normal Tissue Concentrations	Not Available
Diseases / Conditions Related to Nutrition	Not Available
Other (Monogenic Disorders)	Not Available
Abnormal Biofluid Concentrations	Not Available
Abnormal Tissue Concentrations	Not Available
Physiological Processes	Not Available

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Introduction

guidelines
The phosphoric acid ester of serine. As a constituent (residue) of proteins, its side chain can undergo O-linked glycosylation. This might be important in explaining some of the devastating consequences of diabetes. It is one of three amino acid residues that are commonly phosphorylated by kinases during cell signalling in eukaryotes. Phosphorylated serine residues are often referred to as phosphoserine. Serine proteases are a common type of protease. Serine, organic compound, one of the 20 amino acids commonly found in animal proteins. Only the L-stereoisomer appears in mammalian protein. It is not essential to the human diet, since it can be synthesized in the body from other metabolites, including glycine. Serine was first obtained from silk protein, a particularly rich source, in 1865. Its name is derived from the Latin for silk, sericum. Serine's structure was established in 1902.