Sphingosine

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Sphingosine
2D structure for Sphingosine
Chemical Name	(2S,3R,4E)-2-amino-4-Octadecene-1,3-diol
Chemical Formula	C₁₈H₃₇NO₂
CAS Number	123-78-4
Chemical Information	HMDB00252
Biochemical Taxonomy	Amino Alcohols
Functional Taxonomy	Not Available
Nutritional Taxonomy	Not Available
Metabolic Pathways	Glycerolipid Metabolism Glycerophospholipid Metabolism Glycosphingolipid Metabolism
Biofluid Location	Blood Urine
Tissue Location	Fibroblasts Intestine Kidney Liver Muscle Neutrophil Platelet Skin Spleen Stratum Corneum Epidermis
Normal Biofluid Concentrations	Blood: 0.050 +/- 0.0013 umol/L Urine: 0.000038485 (0.0000375-0.00003947) umol/mmol creatinine
Normal Tissue Concentrations	Not Available
Diseases / Conditions Related to Nutrition	Not Available
Other (Monogenic Disorders)	Not Available
Abnormal Biofluid Concentrations	Not Available
Abnormal Tissue Concentrations	Not Available
Physiological Processes	Not Available

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Introduction

guidelines
A 18-carbon amino alcohol with a long unsaturated hydrocarbon chain. Sphingosine and its derivative sphinganine are the major bases of the sphingolipids in mammals. (Dorland, 28th ed.) Sphingosine can be phosphorylated in vivo via two kinases, sphingosine kinase type 1 and sphingosine kinase type 2. This leads to the formation of sphingosine-1-phosphate, a potent signaling lipid.(Wikipedia)