Pyridoxine

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Pyridoxine
2D structure for Pyridoxine
Chemical Name	5-hydroxy-6-methyl-3,4-Pyridinedimethanol
Chemical Formula	C₈H₁₁NO₃
CAS Number	65-23-6
Chemical Information	HMDB00239
Biochemical Taxonomy	Pyridoxals and Derivatives
Functional Taxonomy	Not Available
Nutritional Taxonomy	Not Available
Metabolic Pathways	Vitamin B6 Metabolism
Biofluid Location	Blood
Tissue Location	Erythrocytes Liver Erythrocyte
Normal Biofluid Concentrations	Blood: 0.025(0.007-0.06) umol/L
Normal Tissue Concentrations	Not Available
Diseases / Conditions Related to Nutrition	Homozygous sickle cell disease
Other (Monogenic Disorders)	Epilepsy, pyridoxine-dependent OMIM: 266100 Hyperoxaluria, primary, type I OMIM: 259900 Pyridoxamine 5-prime-phosphate oxidase deficiency OMIM: 610090
Abnormal Biofluid Concentrations	Blood (Homozygous sickle cell disease): 0.119 +/- 0.038 uM
Abnormal Tissue Concentrations	Not Available
Physiological Processes	Not Available

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Introduction

guidelines
The 4-methanol form of vitamin B6 which is converted to pyridoxal phosphate which is a coenzyme for synthesis of amino acids, neurotransmitters (serotonin, norepinephrine), sphingolipids, aminolevulinic acid. Although pyridoxine and Vitamin B6 are still frequently used as synonyms, especially by medical researchers, this practice is erroneous and sometimes misleading (EE Snell; Ann NY Acad Sci, vol 585 pg 1, 1990). Pyridoxine is one of the compounds that can be called vitamin B6. Pyridoxine assists in the balancing of sodium and potassium as well as promoting red blood cell production. It is linked to cancer immunity and helps fight the formation of homocysteine. It has been suggested that Pyridoxine might help children with learning difficulties, and may also prevent dandruff, eczema, and psoriasis. In addition, pyridoxine can help balance hormonal changes in women and aid in immune system. Lack of pyridoxine may cause anemia, nerve damage, seizures, skin problems, and sores in the mouth. -- Wikipedia Deficiency, though rare because of widespread distribution in foods, leads to the development of peripheral neuritis in adults and affects the central nervous system in children (DOSE - 3rd edition)