Inosine

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Inosine
2D structure for Inosine
Chemical Name	9-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-3H-purin-6-one
Chemical Formula	C₁₀H₁₂N₄O₅
CAS Number	58-63-9
Chemical Information	HMDB00195
Biochemical Taxonomy	Nucleosides
Functional Taxonomy	Not Available
Nutritional Taxonomy	Not Available
Metabolic Pathways	Nicotinate and Nicotinamide Metabolism Purine Metabolism
Biofluid Location	Blood Cellular Cytoplasm Cerebrospinal Fluid (CSF) Pericardial Effusion
Tissue Location	Erythrocyte Fibroblasts Intestine Kidney Nerves Pancreas Placenta Platelet Spleen Testes Brain
Normal Biofluid Concentrations	Blood: 0.05 +/- 0.01 uM Blood: 0.604 (0.102-1.81) uM Blood: 5.0 +/- 0.8 uM Blood: 5.0 +/- 6.3 uM Cellular Cytoplasm: 1 uM Cerebrospinal Fluid (CSF): 0.6 (0.0-1.2) uM Cerebrospinal Fluid (CSF): 0.64 +/- 0.35 uM Pericardial Effusion: 0.347 (0.159 - 1.037) uM
Normal Tissue Concentrations	Not Available
Diseases / Conditions Related to Nutrition	Acute and severe illness Coronary Artery Disease Degenerative disc disease Patients with Canavan disease Patients with Chronic Renal Failure
Other (Monogenic Disorders)	Not Available
Abnormal Biofluid Concentrations	Blood (Acute and severe illness): 0.13 +/- 0.10 uM Blood (Patients with Canavan disease): 0.68 +/- 0.47 umol/L Blood (Patients with Chronic Renal Failure): 1.6 +/- 0.4 umol/L Cerebrospinal Fluid (CSF) (Degenerative disc disease): 0.70 (0.60-0.80) uM Pericardial Effusion (Coronary Artery Disease): 0.658 (0.321 - 1.331) uM
Abnormal Tissue Concentrations	Not Available
Physiological Processes	Not Available

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Introduction

guidelines
A purine nucleoside that has hypoxanthine linked by the N9 nitrogen to the C1 carbon of ribose. It is an intermediate in the degradation of purines and purine nucleosides to uric acid and in pathways of purine salvage. It also occurs in the anticodon of certain transfer RNA molecules. (Dorland, 28th ed)