Glyceric acid

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Glyceric acid
2D structure for Glyceric acid
Chemical Name	2,3-dihydroxypropanoic acid
Chemical Formula	C₃H₆O₄
CAS Number	473-81-4
Chemical Information	HMDB00139
Biochemical Taxonomy	Hydroxy Acids
Functional Taxonomy	Not Available
Nutritional Taxonomy	Not Available
Metabolic Pathways	Bile Acid Biosynthesis Butanoate Metabolism Fatty Acid Metabolism Glycerolipid Metabolism Glycolysis Glyoxylate and Dicarboxylate Metabolism Lysine Degradation Propanoate Metabolism Pyruvate Metabolism Valine, Leucine and Isoleucine Degradation
Biofluid Location	Blood Cerebrospinal Fluid (CSF) Urine
Tissue Location	Not Available
Normal Biofluid Concentrations	Blood: 10.0 (0.0-24.0) uM Cerebrospinal Fluid (CSF): 34.0+/- 34.0 uM Urine: 18.9 umol/mmol creatinine Urine: 20.4 umol/mmol creatinine Urine: 3.5 (2.8 - 4.2) umol/mmol creatinine Urine: 3.5 umol/mmol creatinine Urine: 4.0 umol/mmol creatinine Urine: 4.1 umol/mmol creatinine Urine: 5.3 umol/mmol creatinine Urine: 8.9 umol/mmol creatinine
Normal Tissue Concentrations	Not Available
Diseases / Conditions Related to Nutrition	Primary Hyperoxaluria II, PH2
Other (Monogenic Disorders)	Hyperoxaluria, primary, type II OMIM: 260000
Abnormal Biofluid Concentrations	Urine (Primary Hyperoxaluria II, PH2): 2360.0 (1.2 - 1450.0) umol/mmol creatinine
Abnormal Tissue Concentrations	Not Available
Physiological Processes	Not Available

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Introduction

guidelines
A colorless syrupy acid, obtained from oxidation of glycerol. It is a compound that is secreted excessively in the urine by patients suffering from D-glyceric aciduria and D-glycerate anemia. Deficiency of human glycerate kinase leads to D-glycerate acidemia/D-glyceric aciduria. Symptoms of the disease include progressive neurological impairment, hypotonia, seizures, failure to thrive and metabolic acidosis.