Guanidoacetic acid

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Guanidoacetic acid
2D structure for Guanidoacetic acid
Chemical Name	N-(aminoiminomethyl)-glycine
Chemical Formula	C₃H₇N₃O₂
CAS Number	352-97-6
Chemical Information	HMDB00128
Biochemical Taxonomy	Amino Acids
Functional Taxonomy	Not Available
Nutritional Taxonomy	Not Available
Metabolic Pathways	Glycerolipid Metabolism Glycerophospholipid Metabolism
Biofluid Location	Blood Cellular Cytoplasm Cerebrospinal Fluid (CSF) Urine
Tissue Location	Kidney Liver Brain
Normal Biofluid Concentrations	Blood: 1.22 +/- 0.40 uM Blood: 2.0 (0.0 - 5.0) uM Blood: 2.8 +/- 0.9 uM Blood: 3.08 (0.87-3.64) uM Cellular Cytoplasm: 2.3 +/- 0.9 uM Cerebrospinal Fluid (CSF): 0.05 +/- 0.03 uM Urine: 15.4 +/- 10.0 umol/mmol creatinine Urine: 74.0 (18.0-130.0) umol/mmol creatinine Urine: 88.5 (18.0-159.0) umol/mmol creatinine Urine: 89.0 (11.0-124.0) umol/mmol creatinine
Normal Tissue Concentrations	Not Available
Diseases / Conditions Related to Nutrition	Not Available
Other (Monogenic Disorders)	Not Available
Abnormal Biofluid Concentrations	Not Available
Abnormal Tissue Concentrations	Not Available
Physiological Processes	Not Available

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Introduction

guidelines
Metabolite in the Urea cycle and metabolism of amino groups, and in the metabolic pathways of several amino acids. This includes glycine, serine, threonine, arginine and proline metabolism. Guanidinoacetic acid is also a precursor of creatine, an essential substrate for muscle energy metabolism.