Fructose 6-phosphate

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Fructose 6-phosphate
2D structure for Fructose 6-phosphate
Chemical Name	[(2R,3R,4S)-2,3,4,6-tetrahydroxy-5-oxo-hexoxy]phosphonic acid
Chemical Formula	C₆H₁₃O₉P
CAS Number	643-13-0
Chemical Information	HMDB00124
Biochemical Taxonomy	Sugar Phosphates
Functional Taxonomy	Not Available
Nutritional Taxonomy	Not Available
Metabolic Pathways	Aminosugars Metabolism Fructose and Mannose Metabolism Galactose Metabolism Glycerolipid Metabolism Glycolysis Glycosphingolipid Metabolism Keratan Sulfate Biosynthesis N-glycan Biosynthesis Starch and Sucrose Metabolism Streptomycin Biosynthesis
Biofluid Location	Blood Cellular Cytoplasm
Tissue Location	Intestine
Normal Biofluid Concentrations	Blood: 10.2 +/- 1.8 uM Blood: 9.9 +/- 2.3 uM Cellular Cytoplasm: 16.0 (13.0-19.0) uM Cellular Cytoplasm: 49.6 uM
Normal Tissue Concentrations	Not Available
Diseases / Conditions Related to Nutrition	Transketolase and transaldolase (TALDO) deficiency
Other (Monogenic Disorders)	Congenital disorder of glycosylation, type IB OMIM: 602579 Glycogen storage disease vII OMIM: 232800
Abnormal Biofluid Concentrations	Blood (Transketolase and transaldolase (TALDO) deficiency): 6.9 (4.86 - 9.01) uM
Abnormal Tissue Concentrations	Not Available
Physiological Processes	Not Available

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Introduction

guidelines
An important intermediate in the Carbohydrates pathway. The interconversion of glucose-6-phosphate and fructose-6-phosphate, the second step of the Embden-Meyerhof glycolytic pathway, is catalyzed by the enzyme phosphoglucose isomerase (PGI). In gluconeogenesis, fructose-6-phosphate is the immediate precursor of glucose-6-phosphate (wikipedia)