Adenosine

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Adenosine
2D structure for Adenosine
Chemical Name	2-(6-aminopurin-9-yl)-5-(hydroxymethyl)oxolane-3,4-diol
Chemical Formula	C₁₀H₁₃N₅O₄
CAS Number	58-61-7
Chemical Information	HMDB00050
Biochemical Taxonomy	Nucleosides
Functional Taxonomy	Not Available
Nutritional Taxonomy	Not Available
Metabolic Pathways	Methionine Metabolism Nicotinate and Nicotinamide Metabolism Purine Metabolism
Biofluid Location	Blood Cellular Cytoplasm Cerebrospinal Fluid (CSF) Urine
Tissue Location	All Tissues
Normal Biofluid Concentrations	Blood: 0.025(0-0.050) uM Blood: 0.2 (0.1-0.3) uM Blood: 0.31 +/- 0.29 uM Cellular Cytoplasm: 1.20 (0.90-1.50) uM Cerebrospinal Fluid (CSF): 0 - 0.1 uM Cerebrospinal Fluid (CSF): 0.01 +/- 0.002 uM Urine: 0.50 (0.09-0.92) umol/mmol creatinine Urine: 17.5+/-14.6 umol/mmol creatinine Urine: 4.7+/-7.0 umol/mmol creatinine
Normal Tissue Concentrations	Not Available
Diseases / Conditions Related to Nutrition	Adenosine Deaminase (ADA) Deficiency Septic shock
Other (Monogenic Disorders)	Not Available
Abnormal Biofluid Concentrations	Blood (Septic shock): 0.114 (0-0.228) uM Urine (Adenosine Deaminase (ADA) Deficiency): 1.33 umol/mmol creatinine
Abnormal Tissue Concentrations	Not Available
Physiological Processes	Not Available

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Introduction

guidelines
A nucleoside that is composed of adenine and d-ribose. Adenosine or adenosine derivatives play many important biological roles in addition to being components of DNA and RNA. For instance, adenosine plays an important role in energy transfer - as adenosine triphosphate (ATP) and adenosine diphosphate (ADP). It also plays a role in signal transduction as cyclic adenosine monophosphate, cAMP. Adenosine itself is both a neurotransmitter and potent vasodilator. When administered intravenously, adenosine causes transient heart block in the AV node. Because of the effects of adenosine on AV node-dependent supraventricular tachycardia, adenosine is considered a class V antiarrhythmic agent.