3-Methoxytyramine

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3-Methoxytyramine
2D structure for 3-Methoxytyramine
Chemical Name	4-(2-aminoethyl)-2-methoxy-phenol
Chemical Formula	C₉H₁₃NO₂
CAS Number	554-52-9
Chemical Information	HMDB00022
Biochemical Taxonomy	Catecholamines and Derivatives
Functional Taxonomy	Not Available
Nutritional Taxonomy	Not Available
Metabolic Pathways	Tyrosine Metabolism
Biofluid Location	Blood Cerebrospinal Fluid (CSF) Urine
Tissue Location	Most Tissues Brain
Normal Biofluid Concentrations	Blood: 0.0025 (0.0016-0.0029) uM Cerebrospinal Fluid (CSF): 0.0014 +/- 0.0002 uM Urine: 0.014 (0.0052-0.028) umol/mmol creatinine
Normal Tissue Concentrations	Not Available
Diseases / Conditions Related to Nutrition	Parkinson's Disease
Other (Monogenic Disorders)	Not Available
Abnormal Biofluid Concentrations	Cerebrospinal Fluid (CSF) (Parkinson's Disease): 0.0005 +/- 0.0003 uM
Abnormal Tissue Concentrations	Not Available
Physiological Processes	Not Available

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Introduction

guidelines
The O-methylated derivative of dopamine. Dopamine is methylated by catechol-O-methyltransferase (COMT) to make 3-Methoxytyramine. This compound can be broken down to homovanillic acid by monoamine oxidase and aldehyde dehydrogenase. Elevated concentrations of this compound are indicated for a variety of brain and carcinoid tumors as well as certain mental disorders.