P-Hydroxyphenylacetic acid

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P-Hydroxyphenylacetic acid
2D structure for P-Hydroxyphenylacetic acid
Chemical Name	2-(4-hydroxyphenyl)acetic acid
Chemical Formula	C₈H₈O₃
CAS Number	156-38-7
Chemical Information	HMDB00020
Biochemical Taxonomy	Aromatic Acids
Functional Taxonomy	Not Available
Nutritional Taxonomy	Not Available
Metabolic Pathways	Glycolysis
Biofluid Location	Blood Cerebrospinal Fluid (CSF) Saliva Urine
Tissue Location	Epidermis Kidney Bladder
Normal Biofluid Concentrations	Blood: 0.230 (0.070-0.390) uM Cerebrospinal Fluid (CSF): 0.05 +/- 0.007 uM Saliva: 7.0 (2.0-10.0) uM Urine: 14 umol/mmol creatinine Urine: 15.3 umol/mmol creatinine Urine: 15.3 umol/mmol creatinine Urine: 20.3 umol/mmol creatinine Urine: 20.3 umol/mmol creatinine Urine: 23 (20-26) umol/mmol creatinine Urine: 24.2 umol/mmol creatinine Urine: 24.2 umol/mmol creatinine Urine: 30 umol/mmol creatinine Urine: 31.4 umol/mmol creatinine Urine: 31.4 umol/mmol creatinine Urine: 36.7 umol/mmol creatinine Urine: 36.7 umol/mmol creatinine
Normal Tissue Concentrations	Not Available
Diseases / Conditions Related to Nutrition	Epileptic Lung Cancer Schizophrenic Spina bifida
Other (Monogenic Disorders)	Not Available
Abnormal Biofluid Concentrations	Cerebrospinal Fluid (CSF) (Epileptic): 0.038 +/- 0.005 uM Cerebrospinal Fluid (CSF) (Schizophrenic): 0.31 +/- 0.0.03 uM Urine (Lung Cancer): 16 +/- 15 umol/mmol creatinine Urine (Spina bifida): 18-150 umol/mmol creatinine
Abnormal Tissue Concentrations	Not Available
Physiological Processes	Not Available

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Introduction

guidelines
An oxidative deaminated metabolite of p-tyramine. Also a metabolite of tyrosine via enteric bacteria. The bacterial origin of this compound was confirmed by the finding that this compound in urine decreased significantly after the use of the antibiotic neomycin.