Deoxyuridine

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Deoxyuridine
2D structure for Deoxyuridine
Chemical Name	1-[4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidine-2,4-dione
Chemical Formula	C₉H₁₂N₂O₅
CAS Number	951-78-0
Chemical Information	HMDB00012
Biochemical Taxonomy	Nucleosides
Functional Taxonomy	DNA Component
Nutritional Taxonomy	Not Available
Metabolic Pathways	Nicotinate and Nicotinamide Metabolism Purine Metabolism
Biofluid Location	Blood Cerebrospinal Fluid (CSF)
Tissue Location	Bone Marrow Fibroblasts Intestine Lymphocyte Most Tissues Muscle Neurons Pancreas Placenta Testis Bladder
Normal Biofluid Concentrations	Blood: 0.052 (0.049-0.056) uM Blood: 0.200 (0.100-0.300) uM Blood: 0.6 +/- 0.6 uM Blood: 0.62 +/- 0.39 uM Cerebrospinal Fluid (CSF): 0 - 0.1 uM
Normal Tissue Concentrations	Not Available
Diseases / Conditions Related to Nutrition	Not Available
Other (Monogenic Disorders)	Not Available
Abnormal Biofluid Concentrations	Not Available
Abnormal Tissue Concentrations	Not Available
Physiological Processes	Not Available

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Introduction

guidelines
2'-Deoxyuridine is a naturally occurring nucleoside. It is similar in chemical structure to uridine, but without the 2'-hydroxyl group. It is considered to be an antimetabolite that is converted to deoxyuridine triphosphate during DNA synthesis. Laboratory suppression of deoxyuridine is used to diagnose megaloblastic anemia due to vitamin B12 and folate deficiencies.