Glucosylceramide (d18:1/12:0)

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Glucosylceramide (d18:1/12:0)
2D structure for Glucosylceramide (d18:1/12:0)
Chemical Name	N-((2S,3R,E)-3-hydroxy-1-((2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yloxy)octadec-4-en-2-yl)dodecanamide
Chemical Formula	C₃₆H₆₉NO₈
CAS Number	85305-87-9
Chemical Information	HMDB04969
Biochemical Taxonomy	Glycolipids
Functional Taxonomy	Not Available
Nutritional Taxonomy	Not Available
Metabolic Pathways	Not Available
Biofluid Location	Blood
Tissue Location	Brain Liver Nerve Cells Spleen Bone Marrow
Normal Biofluid Concentrations	Blood: 3.6 (2.5-7.2) umol/L
Normal Tissue Concentrations	Not Available
Diseases / Conditions Related to Nutrition	Obese patients
Other (Monogenic Disorders)	Not Available
Abnormal Biofluid Concentrations	Blood (Obese patients): 4.3 (2.9-5.0) umol/L
Abnormal Tissue Concentrations	Not Available
Physiological Processes	Not Available

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Introduction

guidelines
A glycosphingolipid (ceramide and oligosaccharide)or oligoglycosylceramide with one or more sialic acids (i.e. n-acetylneuraminic acid) linked on the sugar chain. It is a component the cell plasma membrane which modulates cell signal transduction events. Gangliosides have been found to be highly important in immunology. Ganglioside GL1a carries a net-negative charge at pH 7.0 and is acidic. Gangliosides can amount to 6% of the weight of lipids from brain, but they are found at low levels in all animal tissues.