From NuGOwiki
The NuGOwiki Metabolite Database is a joint initiative of NuGO and HMDB
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| D-Pipecolic acid | |
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| Chemical Name | (2R)-piperidine-2-carboxylic acid |
| Chemical Formula | C6H11NO2 |
| CAS Number | 1723-00-8 |
| Chemical Information | HMDB05960 |
| Biochemical Taxonomy |
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| Functional Taxonomy | Not Available |
| Nutritional Taxonomy | Not Available |
| Metabolic Pathways | Not Available |
| Biofluid Location |
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| Tissue Location | Not Available |
| Normal Biofluid Concentrations |
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| Normal Tissue Concentrations | Not Available |
| Diseases / Conditions Related to Nutrition |
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| Other (Monogenic Disorders) |
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| Abnormal Biofluid Concentrations |
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| Abnormal Tissue Concentrations | Not Available |
| Physiological Processes | Not Available |
| Authors: | |
| Affiliations: |
Contents |
Introduction
guidelines
D-Pipecolic acid is a normal human metabolite found in human biofluids. Normal adults excrete pipecolic acid primarily as the D-enantiomer even though it is present in the blood stream mainly as the L-enantiomer. It is believed that D-Pipecolic acid originates from the metabolism of intestinal bacteria and from dietary sources. High levels of D-Pipecolic acid are not found in plasma, but they are increased in urine of patients with chronic liver disease. (PMID: 6501504, 6490790, 11719476, 8398594)
Biological Function
Catabolism
Diseases / Conditions Related to Nutrition
- Patients with Chronic Hepatic Encephalopathy
- Patients with Uremia
Other (Monogenic) Disorders
- Peroxisomal acyl-coa oxidase deficiency OMIM: 264470