D-Lactic acid

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D-Lactic acid
2D structure for D-Lactic acid
Chemical Name	(2R)-2-hydroxypropanoic acid
Chemical Formula	C₃H₆O₃
CAS Number	10326-41-7
Chemical Information	HMDB01311
Biochemical Taxonomy	Hydroxy Acids
Functional Taxonomy	Not Available
Nutritional Taxonomy	Not Available
Metabolic Pathways	Pyruvate Metabolism Starch and Sucrose Metabolism
Biofluid Location	Blood Urine
Tissue Location	Brain Epidermis Fibroblasts Gut Intestine Liver Muscle Neurons Placenta Platelet Skeletal Muscle Skin Spleen Stratum Corneum Testes Testis Bladder
Normal Biofluid Concentrations	Blood: 11.0 +/- 1.2 umol/L Urine: 23.00 uM
Normal Tissue Concentrations	Not Available
Diseases / Conditions Related to Nutrition	Diabetic patients
Other (Monogenic Disorders)	Leigh syndrome OMIM: 256000 Mitochondrial complex IV deficiency OMIM: 220110 Myopathy with deficiency of succinate dehydrogenase and aconitase OMIM: 255125 Pyruvate dehydrogenase e3-binding protein deficiency OMIM: 245349 Pyruvate dehydrogenase phosphatase deficiency OMIM: 608782
Abnormal Biofluid Concentrations	Blood (Diabetic patients): 20.0 +/- 1.3 umol/L
Abnormal Tissue Concentrations	Not Available
Physiological Processes	Not Available

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Introduction

guidelines
D-Lactic acid is the end product of the enzyme Glyoxalase II ([EC:3.1.2.6] hydroxyacyl-glutathione hydrolase) which converts the intermediate substrate S-lactoyl-glutathione to reduced glutathione and D-lactate. (OMIM 138790)