D-Glucuronic acid

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D-Glucuronic acid
2D structure for D-Glucuronic acid
Chemical Name	(2S,3S,4S,5R,6S)-3,4,5,6-tetrahydroxyoxane-2-carboxylic acid
Chemical Formula	C₆H₁₀O₇
CAS Number	6556-12-3
Chemical Information	HMDB00127
Biochemical Taxonomy	Not Available
Functional Taxonomy	Not Available
Nutritional Taxonomy	Carbohydrates
Metabolic Pathways	Glutathione Metabolism Prostaglandin and Leukotriene Metabolism Pyruvate Metabolism
Biofluid Location	Blood Urine
Tissue Location	Liver
Normal Biofluid Concentrations	Blood: 165.0 +/- 23.0 uM Blood: 165.0 +/- 32.0 uM Urine: 30.5 umol/mmol creatinine Urine: 33.8 +/- 21.0 umol/mmol creatinine Urine: 5.9 umol/mmol creatinine Urine: 55.8 umol/mmol creatinine
Normal Tissue Concentrations	Not Available
Diseases / Conditions Related to Nutrition	Not Available
Other (Monogenic Disorders)	Infantile sialic acid storage disorder OMIM: 269920
Abnormal Biofluid Concentrations	Not Available
Abnormal Tissue Concentrations	Not Available
Physiological Processes	Not Available

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Introduction

guidelines
Glucuronic acid is a carboxylic acid that has the structure of a glucose molecule that has had its sixth carbon atom (of six total) oxidized. The salts of glucuronic acid are known as glucuronates. Glucuronic acid is highly soluble in water. In the animal body, glucuronic acid is often linked to poisonous substances to allow for subsequent elimination, and to hormones to allow for easier transport. These linkages involve O-glycosidic bonds. The process is known as glucuronidation, and the resulting substances are known as glucuronides (or glucuronosides). Glucuronidation uses UDP-glucuronic acid (glucuronic acid linked via a glycosidic bond to uridine diphosphate) as an intermediate. UDP-glucuronic acid is formed in the liver of all animals.