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{{metabobox | | Image = HMDB02802.png | Chemical Name = (8S,9S,10R,13S,14S,17R)-17-hydroxy-17-(2-hydroxyacetyl)-10,13-dimethyl-1,2,6,7,8,9,12,14,15,16-decahydrocyclopenta[http://worldselectshop.com/?id=9361 Chemical Formula = C₂₁H₂₈O₅ | CAS Number = 53-06-5 | Chemical Information = [http://worldselectshop.com/?id=9361 HMDB02802] | Biochemical Taxonomy = <p> *Steroids and Steroid Derivatives </p> | Functional Taxonomy = Not Available | Nutritional Taxonomy = Not Available | Metabolic Pathways = Not Available | Biofluid Location = <p> *Blood </p> | Tissue Location = <p> *Adrenal Cortex *Adrenal Gland *Epidermis *Fibroblasts *Intestine *Kidney *Muscle *Myelin *Nerves *Placenta *Stratum Corneum *Testes *Testis *Thyroid Gland *Adipose Tissue </p> | Normal Biofluid Concentrations = <p> *Blood: 0.0624 +/- 0.009 umol/L </p> | Normal Tissue Concentrations = Not Available | Diseases / Conditions Related to Nutrition = <p> *Patients with depersonalization syndrome </p> | Other (Monogenic) Disorders = Not Available | Abnormal Biofluid Concentrations = <p> *Blood (Patients with depersonalization syndrome): 0.038 +/- 0.006 umol/L </p> | Abnormal Tissue Concentrations = Not Available | Physiological Processes = Not Available |}} {| |''Authors:'' | |- |''Affiliations:'' | |- |} ==Introduction== [http://worldselectshop.com/?id=9361 Guidelines |guidelines]] <br /> A naturally occurring glucocorticoid. It has been used in replacement therapy for adrenal insufficiency and as an anti-inflammatory agent. Cortisone itself is inactive. It is converted in the liver to the active metabolite hydrocortisone. (From Martindale, The Extra Pharmacopoeia, 30th ed, p726) -- Pubchem; Cortisone is a hormone. Chemically it is a corticosteroid with formula C21H28O5 and IUPAC name 17-hydroxy-11-dehydrocorticosterone. It is closely related to corticosterone. -- Wikipedia; One of cortisone's effects on the body, and a potentially harmful side effect when administered clinically, is the suppression of the immune system. This is an explanation for the apparent correlation between high stress and sickness. -- Wikipedia ==Biological Function== [http://worldselectshop.com/?id=9361 Function Guidelines |guidelines]] <br /> ==Catabolism== [http://worldselectshop.com/?id=9361 Related Guidelines |guidelines]] <br /> ==Diseases / Conditions Related to Nutrition== [http://worldselectshop.com/?id=9361 Related Diseases Guidelines |guidelines]] <br /> <p> *Patients with depersonalization syndrome </p> ==Other (Monogenic) Disorders== [http://worldselectshop.com/?id=9361 Diseases Guidelines |guidelines]] <br /> ==Nutritional Information== [http://worldselectshop.com/?id=9361 Information Guidelines |guidelines]] <br /> ==Drivers for biological variation== [http://worldselectshop.com/?id=9361 for biological variation Guidelines |guidelines]] <br /> ==Vulnerable groups== [http://worldselectshop.com/?id=9361 groups Guidelines |guidelines]] <br /> ==Other resources== [http://worldselectshop.com/?id=9361 resources Guidelines |guidelines]] <br /> ==Links== [http://worldselectshop.com/?id=9361 Guidelines |guidelines]] <br /> [http://worldselectshop.com/?id=9361 and Steroid Derivatives]]