Chenodeoxycholic acid glycine conjugate

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Chenodeoxycholic acid glycine conjugate
2D structure for Chenodeoxycholic acid glycine conjugate
Chemical Name N-[(3a,5b,7a)-3,7-dihydroxy-24-oxocholan-24-yl]-Glycine
Chemical Formula C26H43NO5
CAS Number 640-79-9
Chemical Information HMDB00637
Biochemical Taxonomy

  • Bile Acids

Functional Taxonomy Not Available
Nutritional Taxonomy Not Available
Metabolic Pathways Not Available
Biofluid Location

  • Bile
  • Blood

Tissue Location Not Available
Normal Biofluid Concentrations

  • Bile: >0.01 uM
  • Blood: 0.06 +/- 0.01 umol/L

Normal Tissue Concentrations Not Available
Diseases / Conditions Related to Nutrition Not Available
Other (Monogenic Disorders) Not Available
Abnormal Biofluid Concentrations Not Available
Abnormal Tissue Concentrations Not Available
Physiological Processes Not Available
Authors:
Affiliations:

Contents

Introduction

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A bile salt formed in the liver from chenodeoxycholate and glycine, usually as the sodium salt. It acts as a detergent to solubilize fats for absorption and is itself absorbed. It is a cholagogue and choleretic.

Biological Function

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Catabolism

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Diseases / Conditions Related to Nutrition

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Other (Monogenic) Disorders

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Nutritional Information

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Drivers for biological variation

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The bile acids glycocholic acid, glycochenodeoxycholic acid and taurochenodeoxycholic acid are associated with glucose homeostasis, shown by Shaham et al (PubMed). These three bile acids (in plasma) changed reproducibly in response to an oral glucose challenge test. The levels more than doubled during the first 30 min. after glucose ingestion and remained elevated for the entire 2 hours.

Vulnerable groups

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Other resources

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Links

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