Cancer Antigen 19-9

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Cancer Antigen 19-9
[[Image:{{{Image}}}\|thumb\|220px\|2D structure for Cancer Antigen 19-9]]
Chemical Name
Chemical Formula
CAS Number
Chemical Information
Biochemical Taxonomy
Functional Taxonomy
Nutritional Taxonomy
Metabolic Pathways
Biofluid Location
Tissue Location
Normal Biofluid Concentrations
Normal Tissue Concentrations
Diseases / Conditions Related to Nutrition
Other (Monogenic Disorders)
Abnormal Biofluid Concentrations
Abnormal Tissue Concentrations
Physiological Processes

Authors:	L. Pellis
Affiliations:	TNO, the Netherlands

1 Introduction
2 Biological Function
3 Catabolism
4 Diseases / Conditions Related to Nutrition
- 4.1 Associated decreased protein/metabolite profile
- 4.2 Associated increased protein/metabolite profile
5 Other (Monogenic) Disorders
6 Nutritional Information
7 Drivers for biological variation
8 Vulnerable groups
9 Other resources
10 Links

Introduction

guidelines

CA 19-9 is a derivative of the Lea blood group antigen present on normal mesenteric epithelium. It is not expressed in Lewis-negative individuals, who represent approximately seven percent of the total population in the U.S. It is of clinical use because it is also expressed, at high levels, in most patients with carcinomas of the pancreas, liver, biliary tract, stomach, colon, and breast. CA 19-9 and carcinoembryonic antigen (CEA) may be used together to help differentiate benign disease from pancreatic carcinoma. Elevations of both are suggestive of neoplasia.