Campesterol

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Campesterol
2D structure for Campesterol
Chemical Name 17-(5,6-dimethylheptan-2-yl)-10,13-dimethyl-2,3,4,7,8,9,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-3-ol
Chemical Formula C28H48O
CAS Number 474-62-4
Chemical Information HMDB02869
Biochemical Taxonomy

  • Steroids and Steroid Derivatives

Functional Taxonomy Not Available
Nutritional Taxonomy Not Available
Metabolic Pathways Not Available
Biofluid Location

  • Blood

Tissue Location

  • Muscle
  • Kidney

Normal Biofluid Concentrations

  • Blood: 17.23 (0.24-87.0) umol/L

Normal Tissue Concentrations Not Available
Diseases / Conditions Related to Nutrition

  • Patients with phytosterolemia

Other (Monogenic Disorders)

Abnormal Biofluid Concentrations

  • Blood (Patients with phytosterolemia): 601.94 +/- 6.49 umol/L

Abnormal Tissue Concentrations Not Available
Physiological Processes Not Available
Authors:
Affiliations:

Contents

Introduction

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As a food additive, phytosterols have cholesterol-lowering properties (reducing cholesterol absorption in intestines), and may act in cancer prevention. Phytosterols naturally occur in small amount in vegetable oils, especially soybean oil. One such phytosterol complex, isolated from vegetable oil, is cholestatin, composed of campesterol, stigmasterol, and brassicasterol, and is marketed as a dietary supplement. Sterols can reduce cholesterol in human subjects by up to 15%.

The mechanism behind phytosterols and the lowering of cholesterol occurs as follows : the incorporation of cholesterol into micelles in the gastrointestinal tract is inhibited, decreasing the overall amount of cholesterol absorbed. This may in turn help to control body total cholesterol levels, as well as modify HDL, LDL and TAG levels. Many margarines, butters, breakfast cereals and spreads are now enriched with phytosterols and marketed towards people with high cholesterol and a wish to lower it. -- Wikipedia

Biological Function

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Catabolism

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Diseases / Conditions Related to Nutrition

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  • Patients with phytosterolemia

Other (Monogenic) Disorders

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Nutritional Information

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Drivers for biological variation

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Vulnerable groups

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Other resources

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Links

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