Aluminum

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Aluminum
2D structure for Aluminum
Chemical Name	aluminum
Chemical Formula	Al
CAS Number	7429-90-5
Chemical Information	HMDB01247
Biochemical Taxonomy	Minerals and Elements
Functional Taxonomy	Not Available
Nutritional Taxonomy	Not Available
Metabolic Pathways	Not Available
Biofluid Location	Blood Cerebrospinal Fluid (CSF)
Tissue Location	Not Available
Normal Biofluid Concentrations	Blood: 0.1 +/- 0.056 uM Blood: 0.185 (0.019-0.482) uM Cerebrospinal Fluid (CSF): 12.1+/-6.33 (7.4-25.9) uM
Normal Tissue Concentrations	Not Available
Diseases / Conditions Related to Nutrition	Alzheimer's patients Multiple Sclerosis Parkinson's Disease
Other (Monogenic Disorders)	Alzheimer disease OMIM: 104300
Abnormal Biofluid Concentrations	Blood (Alzheimer's patients): .0823 +/- .046 uM Blood (Multiple Sclerosis): 0.89 +/- 0.79 uM Blood (Parkinson's Disease): 0.11 +/- 0.00061 uM
Abnormal Tissue Concentrations	Not Available
Physiological Processes	Not Available

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Introduction

guidelines
Aluminium is a soft, lightweight metal with appearance ranging from silvery to dull gray, depending on the surface roughness. Data indicate that aluminum contaminates much of the raw material used to manufacture solutions used for intravenous nutritional support of hospitalized and ambulatory patients, and that pharmaceutical manufacturers have only recently obtained the technology necessary to detect aluminum contamination of their products. As a result, aluminum bypassed normal barriers and entered the blood, accumulating in tissues such as bone, liver and the central nervous system with toxic consequences. Now that the FDA has finally issued a rule governing aluminum contamination in these solutions, manufacturers will need to develop methods to minimize such contamination; scientists should also realize that when data they obtain indicate a serious problem in the manufacturing sector they should be sure that the problem is properly addressed. (PMID: 16198633)