5alpha-Pregnane-3,20-dione

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5alpha-Pregnane-3,20-dione
2D structure for 5alpha-Pregnane-3,20-dione
Chemical Name	(5S,8R,9S,10S,13R,14S,17S)-17-acetyl-10,13-dimethyl-1,2,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydrocyclopenta[a]phenanthren-3-one
Chemical Formula	C₂₁H₃₂O₂
CAS Number	566-65-4
Chemical Information	HMDB03759
Biochemical Taxonomy	Steroids and Steroid Derivatives
Functional Taxonomy	Not Available
Nutritional Taxonomy	Not Available
Metabolic Pathways	Not Available
Biofluid Location	Blood
Tissue Location	Testes Testis Fibroblasts
Normal Biofluid Concentrations	Blood: 0.017 +/- 0.005 uM Blood: 0.05 +/- 0.02 uM
Normal Tissue Concentrations	Not Available
Diseases / Conditions Related to Nutrition	Depressed pregnant Psychiatric patient
Other (Monogenic Disorders)	Not Available
Abnormal Biofluid Concentrations	Blood (Depressed pregnant): 0.023 +/- 0.008 uM Blood (Psychiatric patient): 0.04 +/- 0.025 uM
Abnormal Tissue Concentrations	Not Available
Physiological Processes	Not Available

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Introduction

guidelines
A biologically active 5-alpha-reduced metabolite of plasma progesterone. It is the immediate precursor of 5-alpha-pregnan-3-alpha-ol-20-one (allopregnanolone), a neuroactive steroid that binds with GABA(A) receptor.