3,4-Dihydroxyphenylglycol

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3,4-Dihydroxyphenylglycol
2D structure for 3,4-Dihydroxyphenylglycol
Chemical Name	4-(1,2-dihydroxyethyl)-1,2-Benzenediol
Chemical Formula	C₈H₁₀O₄
CAS Number	28822-73-3
Chemical Information	HMDB00318
Biochemical Taxonomy	Alcohols and Polyols
Functional Taxonomy	Not Available
Nutritional Taxonomy	Not Available
Metabolic Pathways	Not Available
Biofluid Location	Blood
Tissue Location	Brain Nerves, Brain Adrenal Medulla
Normal Biofluid Concentrations	Blood: 0.006 +/- 0.0016 umol/L Blood: 0.008 +/- 0.005 uM Blood: 0.009 +/- 0.003 uM
Normal Tissue Concentrations	Not Available
Diseases / Conditions Related to Nutrition	Menkes Disease
Other (Monogenic Disorders)	Not Available
Abnormal Biofluid Concentrations	Blood (Menkes Disease): 0.002 +/- 0.001 uM Blood (Menkes Disease): 0.004 +/- 0.002 uM
Abnormal Tissue Concentrations	Not Available
Physiological Processes	Not Available

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Introduction

guidelines
3,4-Dihydroxyphenylglycol (DOPEG)is a normal norepinephrine metabolite present in CSF, plasma and urine in human (PMID 6875564). In healthy individuals there is a tendency for free DOPEG to increase and for conjugated DOPEG to decrease with age; plasmatic DOPEG levels are significantly lower in depressed patients as compared to healthy controls (PMID 6671452)