2-Phosphoglyceric acid

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2-Phosphoglyceric acid
2D structure for 2-Phosphoglyceric acid
Chemical Name 3-hydroxy-2-phosphonooxypropanoic acid
Chemical Formula C3H7O7P
CAS Number 2553-59-5
Chemical Information HMDB00362
Biochemical Taxonomy

  • Acyl Phosphates

Functional Taxonomy Not Available
Nutritional Taxonomy Not Available
Metabolic Pathways Not Available
Biofluid Location

  • Blood
  • Cellular Cytoplasm

Tissue Location Not Available
Normal Biofluid Concentrations

  • Blood: 1.6 +/- 2.5 uM
  • Cellular Cytoplasm: 14.0 (9.0-19.0) uM

Normal Tissue Concentrations Not Available
Diseases / Conditions Related to Nutrition Not Available
Other (Monogenic Disorders) Not Available
Abnormal Biofluid Concentrations Not Available
Abnormal Tissue Concentrations Not Available
Physiological Processes Not Available
Authors:
Affiliations:

Contents

Introduction

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2-Phosphoglyceric acid (2PGA) is a glyceric acid which serves as the substrate in the ninth step of glycolysis. It is catalyzed by enolase into phosphoenolpyruvate (PEP), the penultimate step in the conversion of glucose to pyruvate. Enolase catalyzes the beta-elimination reaction in a stepwise manner wherein OH- is eliminated from C3 of a discrete carbanion (enolate) intermediate. This intermediate is created by removal of the proton from C2 of 2PGA by a base in the active site. (PMID: 8994873, wikipedia)

Biological Function

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Catabolism

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Diseases / Conditions Related to Nutrition

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Other (Monogenic) Disorders

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Nutritional Information

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Drivers for biological variation

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Vulnerable groups

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Other resources

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Links

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