16a-Hydroxyestrone

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16a-Hydroxyestrone
2D structure for 16a-Hydroxyestrone
Chemical Name (16a)-3,16-dihydroxy-Estra-1,3,5(10)-trien-17-one
Chemical Formula C18H22O3
CAS Number 566-76-7
Chemical Information HMDB00335
Biochemical Taxonomy

  • Steroids and Steroid Derivatives

Functional Taxonomy Not Available
Nutritional Taxonomy Not Available
Metabolic Pathways

  • Androgen and Estrogen Metabolism

Biofluid Location

  • Blood

Tissue Location Not Available
Normal Biofluid Concentrations

  • Blood: 0.00078 (0.00076-0.00081) umol/L

Normal Tissue Concentrations Not Available
Diseases / Conditions Related to Nutrition

  • Patients with breast cancer

Other (Monogenic Disorders) Not Available
Abnormal Biofluid Concentrations

  • Blood (Patients with breast cancer): 0.000817 (0.0008-0.00084) umol/L

Abnormal Tissue Concentrations Not Available
Physiological Processes Not Available
Authors:
Affiliations:

Contents

Introduction

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Estrone (also oestrone) is an estrogenic hormone secreted by the ovary. Its molecular formula is C18H22O2. estrone has a melting point of 254.5 degrees Celsius. estrone is one of the three estrogens, which also include estriol and estradiol. estrone is the least prevalent of the three hormones, estradiol being prevalent almost always in a female body, estriol being prevalent primarily during pregnancy. estrone sulfate is relevant to health and disease due to its conversion to estrone sulfate, a long-lived derivative of estrone. estrone sulfate acts as a pool of estrone which can be converted as needed to the more active estradiol.

Biological Function

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Catabolism

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Diseases / Conditions Related to Nutrition

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  • Patients with breast cancer

Other (Monogenic) Disorders

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Nutritional Information

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Drivers for biological variation

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Vulnerable groups

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Other resources

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Links

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