16-a-Hydroxypregnenolone

From NuGOwiki

The NuGOwiki Metabolite Database is a joint initiative of NuGO and HMDB

Taxonomy Navigation Box; search by

16-a-Hydroxypregnenolone
2D structure for 16-a-Hydroxypregnenolone
Chemical Name	3b,16a-Dihydroxypreg-5-en-20-one
Chemical Formula	C₂₁H₃₂O₃
CAS Number	520-88-7
Chemical Information	HMDB00315
Biochemical Taxonomy	Steroids and Steroid Derivatives
Functional Taxonomy	Not Available
Nutritional Taxonomy	Not Available
Metabolic Pathways	Not Available
Biofluid Location	Blood Urine
Tissue Location	Umbilical cord
Normal Biofluid Concentrations	Blood: 16.1 +/- 2.3 uM Blood: 2.07 +/- 0.53 uM Urine: 0.05 (0.0 - 0.1) umol/mmol creatinine
Normal Tissue Concentrations	Not Available
Diseases / Conditions Related to Nutrition	Congenital adrenal hyperplasia due to 21-hydroxylase deficiency
Other (Monogenic Disorders)	Not Available
Abnormal Biofluid Concentrations	Urine (Congenital adrenal hyperplasia due to 21-hydroxylase deficiency): 0.4 (0.2 -0.6) uM
Abnormal Tissue Concentrations	Not Available
Physiological Processes	Not Available

Authors:
Affiliations:

Introduction

guidelines
16-a-Hydroxypregnenolone is a normal urinary metabolite with increased total excretion in newborn infants with congenital adrenal hyperplasia due to 21-hydroxylase deficiency. (PMID 6980322)