11-Dehydro-thromboxane B2

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11-Dehydro-thromboxane B2
2D structure for 11-Dehydro-thromboxane B2
Chemical Name	7-[(2S,3S,4S)-4-hydroxy-2-[(3S)-3-hydroxyoct-1-enyl]-6-oxo-oxan-3-yl]hept-5-enoic acid
Chemical Formula	C₂₀H₃₂O₆
CAS Number	67910-12-7
Chemical Information	HMDB04242
Biochemical Taxonomy	Prostanoids
Functional Taxonomy	Not Available
Nutritional Taxonomy	Not Available
Metabolic Pathways	Not Available
Biofluid Location	Blood Urine
Tissue Location	Platelet
Normal Biofluid Concentrations	Blood: 0.0027 (0.0021-0.0035) umol/L Urine: 0.000165 +/- 0.0000544 umol/mmol creatinine
Normal Tissue Concentrations	Not Available
Diseases / Conditions Related to Nutrition	unstable angina
Other (Monogenic Disorders)	Not Available
Abnormal Biofluid Concentrations	Urine (unstable angina): 0.000073.3 +/- 0.0000266 umol/mmol creatinine
Abnormal Tissue Concentrations	Not Available
Physiological Processes	Not Available

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Introduction

guidelines
11-Dehydro-thromboxane B2, a stable thromboxane metabolite, is a full agonist of chemoattractant receptor-homologous molecule expressed on TH2 cells (CRTH2) in human eosinophils and basophils. Given its production in the allergic lung, antagonism of the 11-dehydro- thromboxane B2/CRTH2axis may be of therapeutic relevance. (PMID 14668348)