(S)-3-Hydroxybutyric acid

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(S)-3-Hydroxybutyric acid
2D structure for (S)-3-Hydroxybutyric acid
Chemical Name (3S)-3-hydroxybutanoic acid
Chemical Formula C4H8O3
CAS Number 6168-83-8
Chemical Information HMDB00442
Biochemical Taxonomy

  • Hydroxy Acids

Functional Taxonomy Not Available
Nutritional Taxonomy Not Available
Metabolic Pathways Not Available
Biofluid Location

  • Blood
  • Urine

Tissue Location

  • Brain
  • Muscle
  • Neurons
  • Skeletal Muscle
  • Adipose Tissue

Normal Biofluid Concentrations

  • Blood: 20.0 (19.0 - 23.0) uM
  • Urine: 5.9 umol/mmol creatinine

Normal Tissue Concentrations Not Available
Diseases / Conditions Related to Nutrition Not Available
Other (Monogenic Disorders)

  • 3-@hydroxy-3-methylglutaryl-coa synthase 2, mitochondrial, deficiency OMIM: 605911

Abnormal Biofluid Concentrations Not Available
Abnormal Tissue Concentrations Not Available
Physiological Processes Not Available
Authors:
Affiliations:

Contents

Introduction

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(S)-3-Hydroxybutyric acid is a normal human metabolite, that has been found elevated in geriatric patients remitting from depression. (PMID 17048218) 3-Hydroxybutyric acid is a ketone body. Like the other ketone bodies (acetoacetate and acetone), levels of 3-Hydroxybutyric acid are raised in ketosis. In humans, 3-Hydroxybutyric acid is synthesized in the liver from acetyl-CoA, and can be used as an energy source by the brain when blood glucose is low.

Biological Function

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Catabolism

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Diseases / Conditions Related to Nutrition

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Other (Monogenic) Disorders

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  • 3-@hydroxy-3-methylglutaryl-coa synthase 2, mitochondrial, deficiency OMIM: 605911

Nutritional Information

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Drivers for biological variation

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Vulnerable groups

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Other resources

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Links

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